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dueraivcev
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Fecha de registro: 14-08-2022
Fecha de nacimiento: January 1
Hora local: 24-05-2024 en 11:50 PM
Estado: (Oculto)


Información sobre dueraivcev
Ingresó: 14-08-2022
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Información adicional sobre dueraivcev
Bio: RNA suppresses NusA from binding to enzyme
It is thought the nucleosome's a-CTD inhibits the exercise of NusA, which is required to bind to RNA. The a-CTD is situated close to the 3' stop of your nascent transcript and interacts While using the nut-web site RNA. Subsequently, NusA helps prevent the nascent RNA from reading with the nascent transcript. This interaction in between NusA and RNA polymerase is necessary to regulate transcription.

The carboxy-terminal region of NusA is necessary for NusA's perform in termination. This region also serves like a binding web site for RNA. A degree mutation within the carboxy-terminal region boosts antitermination by NusA. However, the deletion of the a-CTD helps prevent NusA from stimulating termination in vitro. That's why, the carboxy-terminal inhibitory domain of NusA might be essential for the antitermination of RNA.

A combination of nusA, rho, and nusG mutations was synthetically lethal. However, lethality was suppressed when nucleoid protein H-NS was expressed inside the cells. Hence, NusA is required for variable-dependent transcription termination and is particularly vital in making a spectrum of termination efficiencies, ranging from polarity to lethality. https://www.zenearth.com/product-category/results-rna-detox/
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